Run it and follow the instructions there, you can either get a basic runtime, or a complete runtime plus a software development kit. Visit the download page to find the latest macOS package. You can use Mono either as a runtime to run existing application, or as an SDK to develop new applications with Mono.
Read the description on MonoMac for more information on how to get started. If you are interested in creating native GUI applications, use the MonoMac bindings and our MonoDevelop add-in. Read below for the options available for GUI application development. You can use Mono on macOS to build server, console and GUI applications. Mono supports macOS version 10.9 (Mavericks) and later.